Occurs when a user attempts to run a process through the process scheduler:
Process Profile defined for user ID %2 is invalid (65,111) The process profile assigned to the user ID is either not valid or blank. Update the User Profile for the user ID in the Maintain Security component with a valid process profile.
PeopleTools > Security > User Profiles
Enter user's ID
Check the Process Profile permission list. It is most likely blank or invalid. Set to something valid like PTPT1000 for example.